Smoking—A Study That Leaves Many Questions Unanswered

Eccentric exercise: many questions unanswered.

LOCOMOTION IS ARGUABLY one of the most ubiquitous and important manifestations of life, equally important to feeding as to escape predators. Evolution came up with three molecular motors to power motion: the actomyosin system Levitsky (11); the microtubule, dynein-based flagellar motors of eukaryotes (13); and the flagellar rotary motors of bacteria (15). All three systems serve propulsion, i.e...

Percutaneous PFO closure, further data but many unanswered questions.

The pace of technological development in interventional congenital cardiology over the last two decades has been fast and relentless. Successful and reliable closure of secundum atrial septal defects in the catheter laboratory translated to interest in the use of similar devices for the occlusion of the patent foramen ovale (PFO), a common remnant of the fetal circulation. The pathological pote...

HIGHLIGHTED TOPIC Eccentric Exercise Eccentric Exercise: Many questions unanswered

LOCOMOTION IS ARGUABLY one of the most ubiquitous and important manifestations of life, equally important to feeding as to escape predators. Evolution came up with three molecular motors to power motion: the actomyosin system Levitsky (11); the microtubule, dynein-based flagellar motors of eukaryotes (13); and the flagellar rotary motors of bacteria (15). All three systems serve propulsion, i.e...

E-Learning: some unanswered questions

Exenatide in Combination Therapy: Small Study, Big Market, and Many Unanswered Questions

Unanswered Questions In the past decade, many new medications have improved our ability to treat patients with type 2 diabetes (1). The pharmaceutical industry has played a key role in this process. Among these novel medications are newly designed insulins, thiazolidinediones (TZDs), meglitinides, orally active inhibitors of the incretin-degrading enzyme dipeptidyl peptidase-IV, and glucagon-li...